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Contact:         Lindsay Polak
                      Technology Transfer Office
                      University of Colorado
                      (303) 735-5518
                      lindsay.polak@cu.edu

FOR IMMEDIATE RELEASE

CU Gene Technology Exclusively Licensed to Colorado Start-up Company

AURORA, Colo. (March 17, 2007) Tissue Genetics, Inc. has secured an exclusive license to proprietary technology developed by Dr. Jeffrey Holt, Todd Professor of Experimental Pathology at the University of Colorado Denver (Anschutz Medical Campus). Tissue Genetics is a predictive medicine company developing diagnostics tools that enable rational drug development and precision therapy in oncology and genetic diseases.  The licensed patent portfolio consists of broad claims that cover methods of detecting over 384 genetic diseases. The University of Colorado Technology Transfer Office (CU TTO) also licensed to the company a patent application for technology that identifies patients who will respond to a new generation of cancer drugs (PARP inhibitors). In 2007 CU TTO began helping the company identify management and legal counsel to facilitate the company’s launch; in November 2007 Jim Bowman (formerly CEO, Encision, Inc; AMEX:ECI) was appointed CEO, and undertook negotiations of the exclusive license agreement executed with CU TTO. The company has been funded thus far by State and Federal grants.  Dr. Holt received a State of Colorado Bioscience Discovery Evaluation Grant (HB1360) to provide initial clinical validation for the intellectual property created in his laboratory.  The company also secured two US Government Small Business Technology Transfer (STTR) awards and two State of Colorado SBIR Matching Funds (HB1060) awards. Tissue Genetics is currently raising their first round of private financing. 

 About the Technology Transfer Office
The CU Technology Transfer Office pursues, protects, packages, and licenses to business the intellectual property generated from research at CU. The TTO provides assistance to faculty, staff, and students, as well as to businesses looking to license or invest in CU technology. For more information about technology transfer at CU, visit www.cu.edu/techtransfer.

About the University of Colorado
The University of Colorado is a three-campus system with campuses in Boulder and Colorado Springs, and a Denver campus located in downtown Denver and at the Anschutz Medical Campus in Aurora. CU is a premier teaching and research university, ranked sixth among public institutions in federal research expenditures by the National Science Foundation. Academic prestige is marked by CU’s four Nobel laureates, seven Mac Arthur “genius” Fellows, 18 astronauts, 19 Rhodes Scholars and CU-Boulder’s ranking of 11th best public university in the world by the Institute for Higher Education. For further information, please visit http://www.cu.edu.